Monday 6 January 2014

When I itches, I scratches

Like the phenomenon of yawning, scientists are fascinated by itching. Itch, like the sensation of burning and pain, are mediated by C fibres of the nervous system - thin, unmyelinated axons found in the peripheral nervous system as well as in the tract that goes up from spinal chord to Thalamus.
It is well known that when a mosquito bites you, histamine is released locally and that it is this histamine that makes you scratch. But in a recent review on the topic in Nature Neuroscience Reviews, you will find a lot more interesting information - including the fact that all itches are not induced by local histamine release.

Nature Reviews Neuroscience 15, 19–31 (2014) doi:10.1038/nrn3641 Published online 20 December 2013

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