Wednesday 23 October 2013

A Step Towards Less Harmful Insecticides

A new generation of mosquito repellents would soon be in the market, if a recent paper in Nature is any indication. Anandshankar Ray and others report that they have identified the specific receptor in the antenna of the fruit fly that responds to a common insect repellent. Then, using computational methods, they screened more than 400,000 molecules that could potentially activate the receptor. And identified more than 100 that could.
Then they selected the ones that have minimum unwanted effects on human beings and tested for their ability to repel mosquitoes. Four of them were found most successful while not affecting humans at all. In fact, they had a mild aroma of grapes. Moreover, they did not dissolve plastics and are therefore more amenable to packaging compared to the existing mosquito repellents  and less costly to produce. Scientists speculate that the repellents may have applications in controlling vector borne diseases and agricultural pests.

Nature(2013) doi:10.1038/nature12594, Published online 02 October 2013

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